Interplay between protein acetylation and ubiquitination controls MCL1 protein stability - ScienceDirect
JCM | Free Full-Text | Genetic Characteristics According to Subgroup of Acute Myeloid Leukemia with Myelodysplasia-Related Changes | HTML
The role of single-cell genomics in human genetics | Journal of Medical Genetics
Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics | Science Signaling
Cancers | Free Full-Text | Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia | HTML
Hymeglusin Enhances the Pro-Apoptotic Effects of Venetoclax in Acute Myeloid Leukemia - Frontiers
Deciphering the molecular mechanism of FLT3 resistance mutations - Georgoulia - 2020 - The FEBS Journal - Wiley Online Library
Cancers | Free Full-Text | Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course | HTML
Targeted activation of GPER enhances the efficacy of venetoclax by boosting leukemic pyroptosis and CD8+ T cell immune function in acute myeloid leukemia | Cell Death & Disease
Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia | Science Advances
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26 | Cell Death & Disease
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia | Science Translational Medicine
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia - ScienceDirect
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors | Nature Communications
Temsirolimus Activates Autophagy and Ameliorates Cardiomyopathy Caused by Lamin A/C Gene Mutation | Science Translational Medicine
RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia - ScienceDirect
Facile and Versatile Surface Functional Polyetheretherketone with Enhanced Bacteriostasis and Osseointegrative Capability for Implant Application | ACS Applied Materials & Interfaces
DNA Origami–Anthraquinone Hybrid Nanostructures for In Vivo Quantitative Monitoring of the Progression of Tumor Hypoxia Affected by Chemotherapy | ACS Applied Materials & Interfaces
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms | Leukemia
Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells | Science Advances
Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy | Nature Communications
The oncogenic roles of NTRK fusions and methods of molecular diagnosis - Cancer Genetics
Tyrosine kinase inhibitor–induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling | Science Translational Medicine
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells | Journal of Medicinal Chemistry
Frontiers | Novel MDM2 Inhibitor XR-2 Exerts Potent Anti-Tumor Efficacy and Overcomes Enzalutamide Resistance in Prostate Cancer
