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PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance | Nature Immunology
Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions | Journal for ImmunoTherapy of Cancer
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease | Nature Medicine
Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice | Aging
Blockade of CCR4 Diminishes Hypersensitivity and Enhances Opioid Analgesia – Evidence from a Mouse Model of Diabetic Neuropathy - ScienceDirect
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses - ScienceDirect
In Vivo Notch Signaling Blockade Induces Abnormal Spermatogenesis in the Mouse | PLOS ONE
Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon | PLOS Neglected Tropical Diseases
Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon | PLOS Neglected Tropical Diseases
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model | Nature Communications
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment | Science Translational Medicine
A2a receptor blockade with CPI-444 enhances efficacy of anti-PD-1... | Download Scientific Diagram
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy - ScienceDirect
Bilateral murine tumor models for characterizing the response to immune checkpoint blockade | Nature Protocols
Combination of IVAX and CTLA-4 blockade led to rejection of higher... | Download Scientific Diagram
TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts | Nature Communications
Intermediate dose of regorafenib shows efficacy when combined with... | Download Scientific Diagram
Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice | Science Advances
Dual blockade of PD1 and CTLA4 has profound anti-tumor effect on E0771... | Download Scientific Diagram
PD-L1 checkpoint blockade delivered by retroviral replicating vector confers anti-tumor efficacy in murine tumor models | Oncotarget
Frontiers | Low-dose immunogenic chemotherapeutics promotes immune checkpoint blockade in microsatellite stability colon cancer
Inhibition of EGFR sensitizes the PD-1 blockade therapy in syngeneic... | Download Scientific Diagram
PARP Targeted Alpha-Particle Therapy Enhances Response to PD-1 Immune-Checkpoint Blockade in a Syngeneic Mouse Model of Glioblastoma | ACS Pharmacology & Translational Science
Photodynamic therapy synergizes with PD-L1 checkpoint blockade for immunotherapy of CRC by multifunctional nanoparticles: Molecular Therapy
Frontiers | Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques
CD16/PD-L1 bi-specific aptamer for cancer immunotherapy through recruiting NK cells and acting as immunocheckpoint blockade: Molecular Therapy - Nucleic Acids